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Kobaktan 2.5% Cobactan Solution *inj (100ml)
Cobactan 2.5 % Cefquinome 100 ml
Composition
Suspension of 25 mg cefquinome per ml (corresponding with 29.64 cefquinome sulphate per ml)
Indications for use
Treatment of infections caused by bacteria sensitive to cefquinome, such as:
Acute E.coli mastitis with signs of systemic involvement
Respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica.
Digital dermatitis, infectious bulbar necrosis, and interdigital necrobacillosis (foul in the foot)
Calf-E.coli septicaemia
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Peni powder for *inj (5pcs. bottle)
Powder for injection
Description
White or white powder with a yellowish tinge, which forms a stable fine suspension with water.
Storage
1 vial of the drug contains the active substance:
benzylpenicillin sodium salt - 1,000,000 IU.
Pharmacological properties
ATC vet classification code QJ01- antibacterial veterinary drugs for systemic use. QJ 01 CE 01 - Benzylpenicillin.
Benzylpenicillin sodium is a bactericidal antibiotic of the penicillin series, which has a detrimental effect on gram-positive and some gram-negative microorganisms: Streptococcus spp . Staphylococcus spp., Bacillus spp., Neisseria spp., Pasteurella spp. and other.
The mechanism of action of the drug is to inhibit the activity of enzymes for the synthesis of peptidoglycan, which is the basis of the cell wall of microorganisms, which leads to delayed reproduction and growth of bacteria.
Penicillin when administered intramuscularly is rapidly absorbed into the blood and distributed in body fluids and tissues; penetrates into the cerebrospinal fluid in small quantities. The maximum concentration of benzylpenicillin in the blood is observed after 30-60 minutes. introduction. In 3-4 hours only traces of an antibiotic are found in blood. To maintain a concentration high enough for a therapeutic effect, injections should be given every 3-4 hours. When administered intravenously, the concentration of penicillin in the blood decreases rapidly. Benzylpenicillin sodium is practically not metabolized in the liver and is excreted unchanged through the kidneys.
