Sarafloxacin - 10g, powder for oral use
Description
Powder white or light yellow dissolves water.
Storage
1 g of the drug contains: sarafloxacin hydrochloride 100 mg.
Pharmacological properties
The antibacterial broad-spectrum drug.
Sarafloxacin Antibiotics fluoroquinolones, mechanism of action is caused by the inhibition of the activity of DNA gyrase (topoisomerase II types of gram-negative bacteria and topoisomerase IV type in certain Gram-positive bacteria) that provide replication of DNA in the nuclei of microbial cells and their subsequent separation, resulting in bacteria multiply.
Effective against gram-positive and gram-negative microorganisms, including resistance to beta-lactam antibiotics, tetracyclines, aminoglycosides and macrolides: E. coli, Salmonella spp., Pasteurella spp., Haemophilus spp., Staphylococcus aureus, Streptococcus spp., Mycoplasma spp., Campylobacter spp., Klebsiella spp., Bordetella spp., Clostridium spp., Yersinia spp., Pseudomonas spp., Enterobacter spp., Ornithobacterium spp. others.
Sarafloxacin is one of the major programs in the treatment of poultry colibacillosis and salmonellosis. It is twice as active against gram-positive bacteria and is four times more active against gram-negative microorganisms than norfloxacin and active against anaerobes for ciprofloxacin.