Doramectin – 10ml
A clear colorless or pale yellow solution for injection.
1 ml of the drug contains the active substance: Doramectin – 10 mg.
Dekostar – ready to use a sterile solution containing the active substance doramectin.
Doramectin – the new substance group of avermectins, has a wide range of system nematodes, insecticidal and acaricidal action larvotsidnymi and ovotsidnymi properties.
Modulates the activity of chloride ions in the nervous system and muscles nematodes and arthropods.
By binding to specific receptors, it increases the permeability of the synaptic membranes for chlorine ions, resulting in a blockade of the activity of nerve and muscle cells, nematodes and arthropods, which causes paralysis and death of the parasites.
At mammals, these receptors are localized only in the central nervous system, as doramectin gematoentsefalny did not penetrate the barrier and, therefore, the recommended doses is safe to mammals. The recommended doses have no mutagenic, teratogenic and embryotoxic action.
Dekostar readily absorbed from the injection site, has high efficiency and no adverse effect on animals. The pharmacokinetic properties of doramectin provide prolonged retention of therapeutic drug concentrations in the blood of animals and protecting them against reinfestation and parasitic diseases for a long time.
Treatment and prevention of diseases of cattle, sheep, pigs, caused by nematodes and ectoparasites: Cattle: gastrointestinal nematodes (adults and larvae of the 4th stage): Ostertagia ostertagi (including inhibited larval stage), O. lyrata, Haemonchus placei, Trichostrongylus axei, T. colubriformis., Cooperia oncophora, C. pectinala, C. punctata, C. sumabada, Nematodirus spathiger, Bunostomum phlebotomum, Strongyloides papillosus. Oesophagostomum radiatum, Trichuris spp .; pulmonary worms (adults and larvae of the 4th stage): Dictyocaulus viviparous; eye worms (mature): Thelazia spp .; subcutaneous gadfly larvae (parasitic stages): Hypoderma bovis, H. Lineatum; lice Haematopinus euresternus, Linognatus vituli, Solenopotes capillatus; itch mites: Psoroptes bovis, Sarcoptes scabiei. It is also used to treat and prevent diseases caused by helminths gastrointestinal Nematodirus helvanicus, Damalinia bovis lice and scabies is Chorioptes bovis. The drug prevents the re-infestation of cattle from: Ostertagia ostertagi – 35 days; Cooperia oncophora -21 hours; Dictyoaculus viviparus – 35 days; Bunostomum phlebotomum – 22 days; Oesophagostomum radiatum – 21 days; Trichostrongilus axei – 28 days; Linognatus vituli – 28 days; Psoroptes bovis – 42 days; Haemonchus placeі – 28 days. To be effective, it is recommended to handle the number of animals commodity preparation Dekostar 1% when translated into pastures and a second 8 weeks. Sheeps: gastrointestinal nematodes (adults and larvae of the 4th stage): Chabertia ovina (mature stage) Cooperia curticei (step L4), C. oncophora, Gaigeria pachycelis, Haemonchus contortus, Nematodes battus (step L4), Ostertagia (Teladorsagia) circumcincta, Oesophagostomum columbianum, Strongyloides papillosus, Tricnostrongylus axei, Trichostrongylus columbiformis, Trichostrongilus vitrinus, Trichuris spp (mature stage);
It acts effectively on the larval stage L4, even those that are naturally insensitive to drugs benzimidazole derivatives. for effective prevention and treatment of animals against adult and larval stages L4 Nematodirus battus recommended dose of 300 mg / kg m. m .; itch mites: Psoroptes ovis; Lung worms: Dictyocaulus filaria (adults); helminths nasal cavity: Oestrus ovis. Pigs: gastrointestinal nematodes (mature and larvae of the 4th stage): Hyostrongylus rubidus, Ascaris suum, Strongyloides ransomi, Oesophagostomum dentatum, Oesophagostomum quadrispinulatum, Lung worms: Metastrongylus spp. (Only mature stage); kidney worms: Stephanurus dentatus (only mature stage); lice: Haematopinus suis; mange mites, Sarcoptes scabiei. Dekostar 1% protects pigs against infestation or reinfestation relatively Sarcoptes scabiei for 18 days.
Recommended dosage: Cattle: 1 ml / 50 kg m. M. (Ekviva¬lentno 200 mg / kg) once subcutaneously in the neck. Sheep: 1 ml / kg 50 m. R. (Equivalent to 200 mg / kg) intramuscularly; in diseases caused by Psoroptes ovis (sheep scab) and Nematodirus battus (mature stage) – 1 ml / 33 kg m. m. (equivalent to 300 mg / kg) intramuscularly. Pigs: 1 ml / kg 33 m. M., Or 0.3 ml / kg of 10 m. R. (Equivalent to 300 mg / kg) intramuscularly. The pigs weighing 16 kg or less (Table I): Body weight of pigs Dose ml <4 0.1 5-7 0.2 8-10 0.3 11-13 0.4 14-16 0.5
Do not use the drug females during lactation, if the milk is used for human consumption. Do not use the preparation cows and heifers tive 60 days prior to calving.
Slaughter of animals for meat after the last injection is permitted for: cattle and sheep through 35 days, pigs – 28 days.
When forced the slaughter of animals meat used to feed carnivorous animals.
Dry place at temperatures up to + 30 ° C. Shelf life – 3 years from the date of manufacture.