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Profiverm 1% euro (10 ml) *inj

$20.89

Profiverm 1% (Ivermectin) injectable

Size: 10ml

Active ingredient: Ivermectin – 10.0 mg

✔ Injectable

✔ For the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms

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Description

Ivermectin – Profiverm:

For the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and sucking lice in cattle, sheep, goats, pigs, dogs
Release Type:
Ampoules of a brown glass of 1, 2 and 5 ml placed in cardboard boxes and bottles of brown glass, closed with a rubber stopper under an aluminum cap of 10, 20, 50, 100 and 200 ml.
 
Application:
Homogeneous, clear colorless to pale yellow, slightly viscous, sterile non-aqueous solution.
СOMPOSITION
1 ml contains active substances: ivermectin – 10 mg; excipients – up to 1 ml
PACKAGING
Ampoules of a brown glass of 1, 2 and 5 ml placed in cardboard boxes and bottles of brown glass, closed with a rubber stopper under an aluminum cap of 10, 20, 50, 100 and 200 ml. DESCRIPTION. 
Homogeneous, clear colorless to pale yellow, slightly viscous, sterile non-aqueous solution.
PHARMACOLOGICAL CHARACTERISTICS.
Ivermectin is a 22,23-dihydro derivative of an avermectin (which is a fermentation product produced by Streptomyces avermitilis) and consists of 2 homologs: B1a and B1b.  It is a parasiticide with nematocidal, insecticidal and acaricidal activity documented in a wide range of domesticated animals. Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action.  Compounds of this class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells.  This leads to an increase in the permeability of the cell membrane to chloride ions with the hyper-polarisation of the nerve or muscle cell resulting in paralysis and death of the parasite. After subcutaneous administration, the drug has the highest capacity for absorption. Ivermectin is metabolized in the liver by oxidation processes, secreted mainly in the feces. Less than 5% of the drug is excreted in the urine.
APPLICATION.
For the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and sucking lice in cattle, sheep, goats, pigs, dogs caused by: cattle: gastrointestinal nematodes – Ostertagia ostertagi, O. lyrata, Trichostrongylus axei, Trichostrongylus columbriformis, Haemonchus placei (including third stage larvae), Nematodirus spp. (mature forms); pulmonary nematodes – Dictyocaulus viviparus (adults and fourth larvae stage); itch tick – Sarcoptes Bovis, Psoroptes bovis; gadfly (in larvae phase) – Hypoderma lineatum, H. Bovis; lice – Linognathus Vitali, Haematopinus eurysternus, Solenopoles capillatus; louse – Bovicola bovis; sheep and goats: gastrointestinal nematodes – Haemonchus contortus, (mature and the third and fourth larvae stage), Trichostrongylus vitrines (mature forms), T. Columbiformes (mature and fourth-stage larvae), Nematodirus filicollis (mature and fourth-stage larvae), Oesophagostomum colombianum, O. venules (mature forms), Charbetia ovina (mature forms), Trichuris ovis (mature forms); pulmonary nematodes – Dictyocaulus filaria (mature and fourth-stage larvae), Protostronlylus spp. (mature forms); itch tick – Sarcoptes scabiei, Psoroptes communis (var. Ovis); nasopharyngeal gadflies – Oestrus ovis (all larval stages); pigs: gastrointestinal nematodes – Ascaris suum, Hyostrongylus rubidus (mature and fourth-stage larvae), Oesophagostomum spp., Strongyloides ransomi (mature forms); pulmonary nematodes – Metastrongylus spp. (mature forms); lice – Haematopinus suis; itch tick – Sarcoptes suis. dogs: nematodes – Dirofilaria immitis, D. repens, Toxascaris leonine, Toxocara canis, Uncinaria stenocephala, Ancylostoma caninum; ticks – Sarcoptes canis, Demodex canis, Otodectes cynotis; lice – Linognathus setosus.
DOSAGE. 
The drug is used once only subcutaneously at doses: cattle, sheep, and goats: 1 ml per 50 kg of body weight (0.2 mg ivermectin per 1 kg of body weight) injected into the area of the shoulder-blade; pigs: 1 ml per 33 kg of body weight (0.3 mg ivermectin per 1 kg of body weight) injected into the middle section of the neck; dogs: 0.1-0.2 ml per 5 kg of body weight (0.2-0.4 mg ivermectin per 1 kg of body weight).
CONTRAINDICATIONS.
The product is for administration only by the subcutaneous route and must not be given via other routes.  It should not be used in other species than those indicated as severe reactions, including fatalities in dogs, may occur. Do not use for dogs of breeds Collie, Bobtail and their hybrids, small breeds of dogs and puppies under 3 months. To ensure the administration of a correct dose, bodyweight should be determined as accurately as possible; the accuracy of the dosing device should be checked.
PRECAUTIONS.
Cattle must not be slaughtered for human consumption until 49 days after the last treatment. This product should not be used in cattle producing milk for human consumption.  The product should not be used in non-lactating dairy cows including pregnant heifers within 60 days of calving. Sheep must not be slaughtered for human consumption until 42 days after the last treatment. This product should not be used in lactating ewes producing milk for human consumption. Pigs must not be slaughtered for human consumption until 28 days after the last treatment.
STORAGE.
A dry, dark place, away from children at the temperature from 5°C to 25°C. The drug is stored separately from food, beverages, including the animal feed.
SHELF-LIFE –
3 years from the date of manufacture.  
 
 

Additional information

Active substances

Dosage form

injection

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