Kefan 10% (ketoprofen)
1 ml of the drug contains:
ketoprofen – 100 mg
The liquid is colorless, transparent.
Nonsteroidal anti-inflammatory drug (NSAID) with a pronounced analgesic and antipyretic effect.
Ketoprofen is a substance from the group of carboxylic acids, derivatives of propionic acid. The mechanism of action is to inhibit the synthesis of prostaglandins and thromboxane and is based on disruption of arachidonic acid metabolism. In therapeutic doses, ketoprofen inhibits mainly COX-II and partially COX-I, providing anti-inflammatory, analgesic, antipyretic and antiendotoxic effects.
After a single intramuscular injection, the maximum concentration of ketoprofen in blood plasma is observed after 30 minutes. Ketoprofen is excreted mainly by the kidneys.
Treatment of cattle, pigs, horses in acute or chronic inflammatory processes of the musculoskeletal system (arthritis, osteoarthritis, bursitis, dislocation, edema, tendovaginitis, trauma, infectious lesions of the hooves), respiratory organs, metritis-mastitis-agalactia, various forms of mastitis, pain of various etiologies (surgery, trauma, colic). Used as an antipyretic in diseases accompanied by hyperthermia and depression.
The drug is administered intramuscularly (intravenously) or intravenously (intravenously) 1 time per day in the following doses:
• cattle (IV or IV) – 0.3 ml per 10 kg of body weight, the course – 1-3 days;
• sport horses (IV) – 1 ml per 45 kg of body weight, the course – 3-5 days (for colic, one injection is enough, re-injection is possible only after additional examination of the animal);
• pigs (in / m) – 0.3 ml per 10 kg of body weight, the course – 1-3 days.
Injections of more than 10 ml are divided into two or more parts and injected in different places.
Do not mix with other drugs in one syringe.
After the last application of the drug, slaughter of pigs for meat is allowed after 4 days, cattle – after 5 days. Meat obtained before this date is disposed of or fed to non-productive animals, depending on the conclusion of the veterinarian. Milk can be consumed without restrictions.
Do not prescribe to animals with hypersensitivity to the active substances of the drug, peptic ulcer of the stomach and duodenum, hemorrhagic syndrome, severe renal or hepatic insufficiency.
Do not use simultaneously with other NSAIDs, glucocorticoids, anticoagulants, diuretics.
In the manufacturer’s package, in a dry, dark place at a temperature of +4 to +25 ° C.