Oxytetracycline (Terramycin) powder
In veterinary medicine, oxytetracycline is used in the form of a base, hydrochloride, and dihydrate. Oxytetracycline base is an amorphous light yellow substance, poorly soluble in water. Oxytetracycline hydrochloride and dihydrate are crystalline substances of yellow color, odorless, bitter taste, readily soluble in water.
Pharmacological properties
Oxytetracycline is a tetracycline antibiotic produced by Streptomyces rimosus. Possesses a wide spectrum of antibacterial action, is active against many gram-positive and gram-negative microorganisms, incl. Escherichia, Salmonella, Staphylococcus, Streptococcus, Rickettsia, and some types of Mycoplasma; does not act on Pseudomonas aeruginosa, Proteus, most fungi, and small viruses. The mechanism of the antibacterial action of oxytetracycline is based on the suppression of protein synthesis of the microbial cell (blockade of ribosome function) and blockade of RNA synthesis.
Application
Treatment of cattle, pigs, and poultry for respiratory and alimentary canal diseases caused by microorganisms sensitive to oxytetracycline.
