Gentamicin sulfate POWDER (Afacin)
1 g of the preparation contains 100 mg of gentamicin sulfate, and as auxiliary substances – colloidal anhydrous silicon 0.5% and lactose up to 100%
Gentamicin powder (Gentamicin) is an antibacterial drug for oral administration, containing 100 mg / g of gentamicin sulfate as an active ingredient, and lactose monohydrate, anhydrous colloidal silicon dioxide as auxiliary components.
Appearance: powder from white to slightly yellowish, odorless, readily soluble in water.
Gentamicin sulfate – belongs to the group of aminoglycoside antibiotics, has a wide spectrum of bactericidal action, is active against most gram-negative and gram-positive microorganisms, including E. coli, Enterobacter spp., Klebsiella pneumoniae, Salmonella spp., Shigella spp., Campylobacter, Pinseudomonas , Proteus, Treponema hyodisenteriae, Corinebacterium spp., Staphylococcus aureus, Bacillus spp., Clostridium spp., Lysteria monocytogenes. The antibiotic has no effect on anaerobic bacteria, fungi, viruses and protozoa. The antimicrobial effect of gentamicin sulfate is based on the inhibition of the formation of peptide bonds during protein synthesis in the ribosomes of a bacterial cell.
When administered orally, the drug is practically not absorbed in the gastrointestinal tract and exerts its effect only in the intestine. Gentamicin sulfate is excreted unchanged from the body, mainly in feces.
Gentamicin P is prescribed to calves, piglets and young poultry for the treatment of colibacillosis, salmonellosis and other gastrointestinal diseases of bacterial etiology caused by microorganisms sensitive to gentamicin, as well as campylobacteriosis and dysentery of pigs and gilts.
Dosage and method of administration:
The drug is administered orally with drinking water at a dose:
calves are injected on the first day – 5 g of the drug per 100 kg of body weight, divided into two doses with an interval of 12 hours; in the next 2-4 days – 4 g of the drug per 100 kg of body weight once a day;
the drug is administered to piglets once a day at a dose:
with colibacillosis – 11 g per 100 l of water for 3 days,
with salmonellosis – 15 g per 100 l of water for 4 days,
with campylobacteriosis and dysentery – 22 g per 100 liters of water for 5 days;
young poultry (broilers, replacement chicks, turkeys from the first days of life) Gentamicin P powder is drunk with water at the rate of 5 g of the drug per 100 l of water for 5-7 days.
During the entire treatment period, young pigs and poultry should receive only water containing Gentamicin powder. For all species of animals, a fresh solution of the drug is prepared daily; the powder must be completely dissolved in water.
Contraindications and warnings:
The antibacterial effect of gentamicin can be significantly reduced by various sodium, calcium and potassium salts (carbonates, sulfates, chlorides, phosphates and nitrates), therefore this drug should not be mixed with any other drug.
The personnel who work with the drug must adhere to the basic rules of hygiene and safety adopted when working with veterinary drugs.
Slaughter of animals and poultry for meat is allowed after 10 days, for internal organs – 14 days after the last use of the drug. Depending on the conclusion of the veterinary doctor, before the specified period, the meat is fed to unproductive animals or disposed of.
Gentamicin-P powder is produced in hermetically sealed laminated foil bags of 50 g, 100 g, 500 g and 1 kg.
The drug is stored in a dry, dark place inaccessible to children at a temperature from 0 to + 30 ° C.
Finished product manufacturer:
Krka, dd, Novo mesto, Shmareška cesta 6, 8501 Novo mesto, Slovenia.