Calphostim, 50 ml
100 ml of the drug contains active substances:
- calcium gluconate – 32.82 g,
- calcium glycerophosphate – 8.13 g,
- magnesium chloride – 4.18 g
Excipients: boric acid, sodium citrate, water for injections.
Pharmacological properties
Kalfostim is a complex drug. The action of the drug is due to the pharmacological properties of the active substances that are part of it.
Calcium is involved in the formation of bone tissue (prevents the risk of rickets and osteodystrophy), in the process of blood clotting, in the regulation of nerve conduction and muscle contractions, in maintaining a stable heart rate. Has tonic, antitoxic effects.
Phosphorus is one of the main elements of bone tissue, nucleoproteins and phospholipids. It participates in all the processes of assimilation in the animal’s body, has a positive effect on metabolism in body tissues.
Magnesium is involved in the metabolism of phosphorus and carbohydrates as a coenzyme. When administered parenterally, it blocks the neuromuscular transmission and prevents the development of seizures.
The active substances of “Kalfostim” are in a physiologically reasonable ratio, well and quickly absorbed by parenteral administration.
“Kalfostim” is low-toxic, well tolerated by animals of different ages, in the recommended doses does not have a local irritant, sensitizing, teratogenic and embryotoxic effects, does not have cumulative properties.
Application
Treatment and prevention of animals with diseases associated with impaired metabolism of calcium, phosphorus and magnesium:
- hypocalcemia (postpartum paresis, rickets in young animals, osteomalacia in older animals); various forms of tetany (transport and pasture tetany, tetany during pregnancy and lactation);
- allergies, toxicosis, postpartum hemoglobinuria, spot disease, urticaria; exanthema, hemorrhagic diathesis, hematuria and myoglobinuria;
- paresis due to calcium and phosphorus deficiency of various etiologies;
- adjuvant therapy for lead, fluoride or oxalic acid intoxication.
Dosage
The drug is administered intravenously, intramuscularly or subcutaneously in a dose of:
| Animal species | Dose in ml per animal | Method of administration |
| Horses weighing up to 500 kg | 80-100 | Intravenously. |
| Cattle weighing up to 500 kg (different ages) | 80-100 | Intravenously. Intramuscularly (maximum dose for administration in one place no more than 25 ml). Subcutaneously (maximum dose for administration in one place no more than 50 ml). |
| Sheep, goats (different ages) | 15-25 | Intravenously. Intramuscularly (maximum dose for administration in one place no more than 15 ml). Subcutaneously. |
| Pigs | 15-25 | Intravenously. Intramuscularly (maximum dose for administration in one place no more than 15 ml). Subcutaneously. |
| Piglets | 2-3 | Intramuscularly. Subcutaneously |
For therapeutic purposes, Kalfostim is prescribed to animals once. Re-use of the drug after 24 hours in the doses listed in the table.
For the prevention of disorders of calcium, phosphorus and magnesium metabolism during pregnancy, lactation, and rickets in young farm animals Calfostim used once in the recommended doses.
Contraindication
Hypercalcemia, acidosis, renal dysfunction, excessive nervous excitement, ventricular fibrillation, hypersensitivity to the components of the drug.
Storage
In a dry, dark and out of reach of children at a temperature of 5 ° C to 25 ° C
Shelf life – 3 years, after the first opening of the bottle – 28 days.
