Onsior Elanco for cats 6 mg (robenacoxib) 1 blister 6 tablets
Onsior tablets for cats contain robenacoxib as an active ingredient – 6 mg / tab. As excipients, Onsior tablets contains: yeast, microcrystalline cellulose, identical beef flavor, powdered cellulose, povidone (K-30), crospovidone, anhydrous colloidal silicon dioxide and magnesium stearate. In appearance, the drug is a round tablet from beige to brown. Onsior tablets for cats are imprinted with NA on one side and imprinted with AK on the other side. The drug is released packaged in 6 tablets in aluminum foil blisters, placed 1, 2, 5 or 10 pieces in cardboard boxes along with instructions for use. Vacation conditions: without a prescription from a veterinarian.
Onsior tablets refers to non-steroidal anti-inflammatory drugs.
Robenacoxib, which is part of the drug, is a non-steroidal anti-inflammatory drug of the coxibs group, is a selective specific inhibitor of COX-2 and has anti-inflammatory and analgesic effects. COX is presented in two forms: COX-1 – a constitutive form of the enzyme – performs protective functions, including in the gastrointestinal tract and kidneys; COX-2, an inducible form of the enzyme, is responsible for the production of mediators, including PGEg, that cause pain, inflammation, and fever. When administered orally, robenacoxib is rapidly absorbed in the intestine, entering the systemic circulation and most organs and tissues; more than 99% of robenacoxib binds to plasma proteins. Its maximum plasma concentration is observed after 0.5 hours, bioavailability is 49% in cats and 62% in dogs when using tablets with food and 84% without food. Robenacoxib is metabolized in the liver, excreted mainly in the bile (about 70% in cats and about 65% in dogs) and partially in the urine; the elimination half-life from the body of dogs is about 1.2 hours, cats – 1.7 hours. Onsior™ tablets, according to the degree of impact on the body, are classified as moderately hazardous substances (hazard class 3 according to GOST 12.1.007).
Onsior tablets are prescribed to dogs and cats as an anti-inflammatory and analgesic drug for inflammatory and pain syndromes of various origins, including acute and chronic diseases of the musculoskeletal system (arthritis, arthrosis, synovitis, dislocations), inflammatory diseases of soft tissues, and also as an analgesic and anti-inflammatory drug in the postoperative period.
Onsior tablets are administered to dogs and cats individually once a day at the doses indicated in the table:
| 6 mg | 5 mg | 10 mg | 20 mg | 40 mg | |
| from 2.5 to 6 kg | 1 tab. | ||||
| from 6 to 12 kg | 2 tab. | ||||
| from 2.5 to 5 kg | 1 tab. | ||||
| from 5 to 10 kg | 1 tab. | ||||
| from 10 to 20 kg | 1 tab | ||||
| from 20 to 40 kg | 1 tab. | ||||
| from 40 to 80 kg | 2 tab. | ||||
It is recommended to give the drug separately from feeding, but, if necessary, the drug can be given with food. Tablets should not be crushed or broken.
Onsior tablets are used in cats during surgical interventions 30 minutes before anesthesia at a dose of 1-2.4 mg per 1 kg of animal weight; treatment can be continued for up to 2 days after surgery; in diseases of the musculoskeletal system, the drug is used up to 6 days. The course of treatment is determined by the attending veterinarian.
As a rule, the duration of treatment is 7 days. If after 10 days there is no clinical improvement, the drug is discontinued.
In case of an overdose of the drug in animals with severe sensitivity to the components of the drug, an upset of the gastrointestinal tract, liver or kidney failure may be observed.
There are no specific means of detoxification, general measures are used to remove the drug from the body.
Features of the action of the drug during its first use and cancellation have not been established.
It is forbidden to use Onsior tablets for pregnant and lactating animals, kittens younger than 4 months of age.
Violation of the recommended interval between injections of the drug should be avoided, as this may lead to a decrease in therapeutic efficacy. In case of missed repeated administration, the drug should be administered as soon as possible in the prescribed dose.
*Kilograms to Pounds conversion table
| Kilograms (kg) | Pounds (lb) | Pounds+Ounces (lb+oz) |
| 0.1 kg | 0.220 lb | 0 lb 3.527 oz |
| 1 kg | 2.205 lb | 2 lb 3.274 oz |
| 5 kg | 11.023 lb | 11 lb 0.370 oz |
| 10 kg | 22.046 lb | 22 lb 0.740 oz |
When using Onsior tablets in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. Cats may experience gastrointestinal disturbances (vomiting, soft stools, or diarrhea) and these symptoms resolve spontaneously and do not require medication. With individual hypersensitivity of the animal to the drug and the appearance of allergic reactions, the use of the drug is stopped and the animal is prescribed antihistamines and symptomatic agents.
It is forbidden to use Onsior tablets in animals in a state of dehydration, hypovolemia and hypotension, as well as in animals weighing less than 2.5 kg. If it is absolutely necessary to prescribe a medicinal product to such animals, treatment is carried out under the constant supervision of a veterinarian. Contraindication to use is the individual hypersensitivity of the animal to the components of the drug. Do not use the drug in animals with severe cardiac, renal and hepatic insufficiency.
Onsior tablets should not be used simultaneously with other non-steroidal anti-inflammatory drugs and within 24 hours after their withdrawal, diuretics, as well as ACE inhibitors and other drugs with a high degree of binding to blood serum proteins due to the likelihood of mutual enhancement of toxic effects. The medicinal product is not intended for use in productive animals.
People with hypersensitivity to the components of the drug should avoid direct contact with Onsior tablets. In case of accidental contact of the medicinal product with the skin or mucous membranes, they should be washed immediately with plenty of water. It is forbidden to use empty containers from under the drug for domestic purposes; it must be disposed of with household waste. When using Onsior tablets, you should follow the general rules of personal hygiene and safety precautions provided for when working with drugs. Do not smoke, drink or eat while working. At the end of work, wash your face and hands thoroughly with soap.
Onsior tablets in the manufacturer’s closed packaging in a place protected from direct sunlight, away from food and feed, at a temperature of 0°C to 25°C. Keep out of the reach of children. The unused medicinal product is disposed of in accordance with the requirements of the legislation. The shelf life of the medicinal product, subject to storage conditions in the manufacturer’s unopened packaging, is 4 years from the date of manufacture. It is forbidden to use Onsior tablets after the expiration date.
