Tylosin powder for pigs, piglets, chickens, broilers, chickens, ducks, turkeys, geese, 1100 g (2,4 lbs)
Composition and description:
Water-soluble granules for oral administration. Farmazin 1000 in 1 g of the drug contains 1000 IU of active tylosin, which corresponds to the content of 1100 mg of the antibiotic tylosin tartrate. The drug is obtained by chemical synthesis and does not contain components of animal and vegetable origin, genetically modified products.
Release form:
Produced packaged in foil sachets of 1100 g. Each package is supplied with instructions for use.
Pharmacological properties:
The active substance Farmazin 1000 tylosin is an antibiotic from the macrolide group, it is active against most gram-positive and some gram-negative bacteria, including staphylococci, streptococci, corynebacteria, clostridia, pasteurell, erysipelothrix, spirochetes, chlamydia, treponema, chiodysentery and mycoplasmas. The mechanism of action of tylosin is to suppress protein synthesis at the ribosomal level.
When administered orally, the antibiotic is rapidly absorbed into the blood from the gastrointestinal tract and penetrates into almost all organs and tissues of the body. The highest concentration of tylosin is achieved in the lungs, liver, mammary glands and kidneys. The therapeutic concentration of the antibiotic after a single application of Farmazin 1000 granules remains in the body for 15-24 hours. In addition, due to the peculiarities of the mechanism of action, farmazin selectively accumulates in tissues with low pH values, that is, in the foci of inflammation, providing a pronounced and targeted effect. Tylosin is excreted from the body mainly with faeces, to a lesser extent – with urine and milk, in laying birds – with eggs.
According to the degree of impact on the body, Farmazin® 1000 belongs to moderately hazardous substances (hazard class 3 according to GOST 12.1.007). In recommended doses, it does not have embryotoxic, teratogenic and carcinogenic effects.
Indications:
It is prescribed for the treatment of poultry and pigs with gastrointestinal and respiratory bacterial infections caused by pathogens sensitive to tylosin.
Doses and route of administration:
Farmazin 1000 is administered orally with drinking water. The antibiotic solution must be in the drinkers constantly during the entire period of use of farmazin. During the treatment period, pigs and poultry should not receive any source of drinking other than medicated water.
Before use, the recommended dose of farmazin is dissolved in a small amount of water (water is added to the granulate), and then this solution is diluted with water to the required concentration.
Avoid exposure to direct sunlight on an aqueous solution of farmazin. The antibiotic solution is prepared daily.
With a therapeutic and prophylactic purpose, Farmazin 1000 is prescribed at a dose of 0.5 g per 1 liter of water to broilers for 3 days, to turkeys for 5 days in the following growing periods:
Species and group of birds | Bird age (days) | ||||
1-3 | 1-5 | 28-29 | 56-57 | 140-141 | |
tribal bird | + | + | + | + | |
industrial herd | + | + | |||
Turkeys | + | ||||
Broiler chickens | + | + |
With mycoplasmosis, dysentery and gastroenterocolitis of bacterial etiology, pigs are prescribed Farmazin 1000 at a dose of 0.25 g per 1 liter of drinking water for 3-10 days.
Avoid skipping the next dose of Farmazin, tk. this may lead to a decrease in the therapeutic efficacy of the drug. If one dose is missed, it should be administered as soon as possible. Further, the interval until the next injection of the drug does not change.
Overdose syndromes have not been identified.
In the event of allergic reactions, the use of the drug is stopped and antihistamines or other symptomatic treatment is prescribed.
Side effects:
When prescribing Farmazin 1000 in accordance with the indications and dosing regimen, adverse reactions and complications are usually not noted.
Allergic reactions to tylosin in pigs are possible, manifested in the form of erythema, pruritus, mild edema with slight prolapse of the rectum, respiratory phenomena, which quickly disappear after discontinuation of the drug. If within 2-3 days there is no noticeable clinical improvement, it is recommended to re-test the sensitivity of microorganisms isolated from sick animals and birds to tylosin or replace Farmazin 1000 with another antibacterial drug.
Contraindications:
Increased individual sensitivity to tylosin. It is forbidden to use farmazin for laying hens and turkeys whose eggs are intended for human consumption.
Special instructions:
Slaughter of pigs and poultry for meat is allowed 5 days after the last use of the drug. The meat of animals compulsorily slaughtered before the expiration of the established period may be used for feeding fur-bearing animals or for the production of meat and bone meal. The eggs of a bird treated with farmazin are not eaten due to the risk of sensitization.
Measures of personal prevention:
When working with Farmazin 1000, it is necessary to follow the general rules of personal hygiene and safety precautions provided for when working with veterinary medicinal products.
When working with the drug, it is forbidden to drink, smoke and eat. After work, wash your hands with soap and water. If Farmazin 1000 gets on the skin and mucous membranes, rinse them with plenty of tap water.
Storage conditions:
With caution (list B). In the manufacturer’s closed packaging, separately from food and feed, in a dry, protected from direct sunlight and out of the reach of children and animals at a temperature of +5°С to +25°С.
Shelf life:
3 years.
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