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Showing all 2 results

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    Kloziver for cattle, sheep, goats (100 ml) *inj

    Original price was: $74.94.Current price is: $62.81.
    Kloziver (closantel,ivermectin) injectable
    Kloziver is a combination drug, comprising closantel and ivermectin. Closantel is a salicylamide’s derivative, providing antiparasitic action. Closantel’s mode of action centers around inhibition of oxidative phosphorylation. Specific action centers around ATP stimulation, leading to stopping of a phosphorylation process and electrons’ transfer, changing suchwise parasite’s energy metabolism. This leads to its death. Ivermectin refers to compounds, which are produced by Streptomices avermitis. Ivermectin’s mode of action on parasite’s body centers around secretion stimulation of GABA (gamma-amino-butyric acid), which binds to special receptors of nerve endings, blocking nerve impulses and causing paralysis and death of a parasite.

    Kloziver (10 ml) inj

    $26.38
    Kloziver (closantel,ivermectin) injectable
    Kloziver is a combination drug, comprising closantel and ivermectin. Closantel is a salicylamide’s derivative, providing antiparasitic action. Closantel’s mode of action centers around inhibition of oxidative phosphorylation. Specific action centers around ATP stimulation, leading to stopping of a phosphorylation process and electrons’ transfer, changing suchwise parasite’s energy metabolism. This leads to its death. Ivermectin refers to compounds, which are produced by Streptomices avermitis. Ivermectin’s mode of action on parasite’s body centers around secretion stimulation of GABA (gamma-amino-butyric acid), which binds to special receptors of nerve endings, blocking nerve impulses and causing paralysis and death of a parasite.

    Ivermectin

    The anti-inflammatory properties of topical ivermectin have been observed in animal models of inflammatory skin processes. Ivermectin also causes death of parasites, mainly through selective binding and high affinity for glutamate-regulated chlorine channels found in nerve and muscle cells of invertebrates. The mechanism of action of ivermectin in the treatment of inflammatory skin lesions in rosacea is not known, but may be associated with both the anti-inflammatory effects of ivermectin and the ability of ivermectin to kill Demodex mites, which, in turn, are a factor causing skin inflammation.