$27.49Original price was: $27.49.$25.18Current price is: $25.18.
Powder for injection
Description
White or white powder with a yellowish tinge, which forms a stable fine suspension with water.
Storage
1 vial of the drug contains the active substance:
benzylpenicillin sodium salt - 1,000,000 IU.
Pharmacological properties
ATC vet classification code QJ01- antibacterial veterinary drugs for systemic use. QJ 01 CE 01 - Benzylpenicillin.
Benzylpenicillin sodium is a bactericidal antibiotic of the penicillin series, which has a detrimental effect on gram-positive and some gram-negative microorganisms: Streptococcus spp . Staphylococcus spp., Bacillus spp., Neisseria spp., Pasteurella spp. and other.
The mechanism of action of the drug is to inhibit the activity of enzymes for the synthesis of peptidoglycan, which is the basis of the cell wall of microorganisms, which leads to delayed reproduction and growth of bacteria.
Penicillin when administered intramuscularly is rapidly absorbed into the blood and distributed in body fluids and tissues; penetrates into the cerebrospinal fluid in small quantities. The maximum concentration of benzylpenicillin in the blood is observed after 30-60 minutes. introduction. In 3-4 hours only traces of an antibiotic are found in blood. To maintain a concentration high enough for a therapeutic effect, injections should be given every 3-4 hours. When administered intravenously, the concentration of penicillin in the blood decreases rapidly. Benzylpenicillin sodium is practically not metabolized in the liver and is excreted unchanged through the kidneys.
Amoxicillin trihydrate - semi-synthetic penicillin, belongs to beta-lactam antibiotics, inhibits the synthesis of bacterial cell walls by inhibiting transpeptidase and carboxypeptidase, which causes a violation of osmotic pressure and the death of microorganisms in the developmental stage.
Potassium clavulanate is a beta-lactam structurally related to penicillins, has little antibacterial activity, but, irreversibly inhibiting a size of beta-lactamases, prevents inactivation of amoxicillin and provides its antibiotic activity against bacteria, usually resistant to other amoxicillin-resistant amoxicillin.