PROVECT for cats 5-8 kg / 11-18 lbs (milbemycin oxime, praziquantel), 3 tablets

Description

Round tablets are biconvex yellowish-white with brown spots.

Storage

The drug is designed for cats with different body weights; each tablet contains the active substances at the rate of 2 mg of milbemycin oxime and 5 mg of praziquantel per kg of body weight of the animal.

Excipients: corn starch, lactose monohydrate, microcrystalline cellulose, povidone, magnesium stearate, colloidal silicon dioxide, meat flavoring, yeast powder.

Pharmacological properties

ATCvet QP54, endectocides (QP54AB51, milbemicini)

PROVECTRA for cats is a combined drug with a wide range of anthelmintic action. Contains active ingredients: milbemycin oxime and praziquantel.

Milbemycin oxime is a macrocyclic lactone obtained by fermentation of Streptomyces hygroscopicus, type Aureolacrimosus, active against larvae and adult nematodes that parasitize the digestive tract of cats, as well as against larvae of nematodes Dirofilaria immitis (microdirophylaria).

The mechanism of action of milbemycin oxime is to increase the permeability of the membranes of nematode nerve and / or muscle cells to chlorine ions, which causes their hyperpolarization. This leads to an irreversible decrease in muscle activity, paralysis and death of parasites.

The maximum concentration of milbemycin oxime in the blood plasma of cats is reached after 2 hours, the bioavailability is about 80%. It is excreted from the body of animals, mostly unchanged.

Praziquantel is a derivative of acylated pyrazinisoquinoline. Praziquantel is active against cestodes and trematodes. Increasing the permeability of parasite cell membranes to calcium ions leads to depolarization of membranes, muscle contraction and damage to the tegument, which leads to the death of helminths and promotes their excretion from animals.

The maximum concentration of praziquantel in the blood plasma of cats is reached after 1 hour, the bioavailability is about 80%, excreted mainly in the form of inactive metabolites in the urine, the half-life is 3 hours.

PROVECTRA for cats by the degree of action on the body belongs to the moderately toxic substances (safety class 3), in the recommended doses does not show sensitizing, embryotoxic and teratogenic effects.

Application

Prevention and treatment of cats in invasions caused by cestodes (larval and adult forms) – Dipylidium caninum, Taenia spp., Echinococcus spp .; nematodes – Ancylostoma tubaeforme, Toxocara cati, Dirofilaria immitis (disease prevention); incl. with combined nematode-cestode invasions.

The drug can also be used to prevent heartworm disease (Dirofilaria immitis), if concomitant treatment against cestodes is recommended.

Dosage

The drug is administered to cats individually once orally with food or forced to the root of the tongue in the minimum therapeutic dose: 2 mg of milbemycin oxime and 5 mg of praziquantel per kg of body weight.

Depending on the weight of the cat, the actual dosage is:

*Kilograms to a Pounds conversion table

Adherence to a diet or special feeding regime is not required. Separation of the tablet is not allowed.

Deworming of cats for therapeutic purposes is carried out according to the indications, for prophylactic purposes – quarterly, as well as before each vaccination and mating in a therapeutic dose. A single therapeutic dose protects cats from Dirofilaria immitis infection for one month. For the subsequent prevention of heartworm disease, it is advisable to use a drug containing one active substance milbemycin oxime.

Peculiarities of the drug’s action during its first use and withdrawal have not been established.

When carrying out deworming it is necessary to adhere to the recommended terms. In case of skipping the next treatment, the drug is resumed in the same dose and according to the same scheme.

Contraindication

Increased individual sensitivity of animals to the components of the drug!

Severe renal and hepatic dysfunction!

Do not use the drug in kittens under 6 weeks of age and/or weighing less than 0.5 kg!

Do not use in depleted and infectious animals!

Reservation

Deworming of animals during pregnancy and lactation is carried out as needed and under the supervision of a veterinarian.

When using the drug strictly adhere to the recommended dosage.

All animals kept together must be treated.

Animals weakened, sick or with impaired renal and hepatic function should be used only under the supervision of a veterinarian with a benefit / risk assessment.

Release form

PET / PE blisters of 1 tablet, packed in cardboard boxes of 2 and 25 pieces.

Storage

The drug is stored in the original packaging of the manufacturer, separately from food and feed, in a dry place, protected from direct sunlight, out of reach of children and animals at a temperature of 15 to 25 ° C.

Expiration date

3 years.

For use in veterinary medicine!