Tylosin is effective against gram-positive and some gram-negative microorganisms: Corynebacterium spp., Clostridium spp., Erysipelothrix spp., Pasteurella spp., Vibrio spp., Leptospira spp., Brucella spp., Neisseria spp., Haemophilus spp... And against rickettsiae (Rickettsia spp.), spirochetes (Spirochaeta (Borrelia anserina, Brachyspira hyodysenteriae)), and mycoplasmas (M. gallisepticum, M. synoviae, M. meleagridis, etc..). In other words, tylosin exhibits bacteriostatic effect by inhibition of protein synthesis (via the irreversible connection with bacterial 50S ribosomal subunits) and microbial cell growth and reproduction, respectively.
Dogs and cats: daily hygienic treatment of the eyes, prevention of cataracts, with acute and chronic catarrhal and serous-catarrhal conjunctivitis with a therapeutic and prophylactic purpose, excessive tearing, inflammation of the mucous membrane, and vascular hyperemia of the eyeball (red-eye syndrome), after injuries and ingress of foreign bodies, age-related dystrophic and degenerative changes in the cornea and retina.
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