Сlosantel 100 mg/ml Solution for INJECTION, 100 ml
BRONTEL
Storage
1 ml of the drug contains:
clozantel – 100 mg
Description
The liquid is light yellow, transparent.
Pharmacological properties
Closantel is a synthetic compound from the group of salicylanides. Inhibits and stops the transfer of electrons, which alters the energy metabolism of parasites and causes their death. It has a wide range of antiparasitic action, active against trematodes, nematodes, mites, lice, rubella and larvae of mosquitoes.
After intramuscular injection is rapidly absorbed, the maximum concentration in the blood is reached after 12 hours and persists for 24-36 hours, therapeutic concentration – for 10-11 days. It is not biotransformed in the body and is excreted mainly unchanged in the feces, and in lactating cows – partly with milk.
Indication
Treatment and prevention of cattle, sheep, goats, dogs, cats with parasitic diseases caused by ecto- and endoparasites of different localization.
Contraindication
Do not prescribe to females in the last third of pregnancy.
Do not use simultaneously with organophosphorus drugs.
Method of application and dosage
Treatment against helminthiasis is carried out at the beginning and end of the stall period, against hypodermatosis – immediately after the flight of geds or when the genus is detected in the spring.
The drug is administered subcutaneously. Intramuscular administration is allowed to cattle. Injection of more than 3 ml is divided into two parts and injected into different places.
In the group method, each batch of the drug is pre-tested on a small number of animals. In the absence of complications, treatment is carried out throughout the herd.
Doses of the drug for different species of animals are listed in the table.
| Animal species and diseases | Dose, ml / 10 kg of body weight | Course of application | |
| Cattle : | |||
| gastrointestinal nematodes – bunostomosis, hemonchosis, esophagostomosis, strongyloidiasis, habertiosis, fasciolosis (mature forms of trematodes) | 0.25 | once | |
| fasciolosis (adult forms and young trematodes over 6 weeks of age), hypodermatosis (larvae of stages 1 and 2) | 0.5 | ||
| sarcoptosis (scabies) – Sarcoptes bovis, Psoroptes bovis, Chorioptes bovis, Demodex bovis | 1 | 2 times in 7 days | |
| larvae of the meat fly – Sarcophagidae, Calliphoridae | 0.25 | once | |
| Sheep, goats : | |||
| bunostomosis, esophagostomosis, trichostrongylosis, habertiosis, estrosis, wolfarthiosis | 0.25 | once | |
| fasciolosis (mature forms and young trematodes over 6 weeks of age) | 0.5 | ||
| demodecosis – Demodex bovis, sarcoptosis (scabies) – Sarcoptes dependent, S.caprae, Psoroptes dependent, Chorioptes dependent, Ch. caprae | 1 | 2 times in 7 days | |
| Dogs : | |||
| hookworm | 0.75 | once | |
| demodicosis | 0.5 | 2 times in 7 days | |
| Cats : | |||
| otodectosis | 0.5-0.7 | 2 times in 7 days | |
*Kilograms to Pounds conversion table
| Kilograms (kg) | Pounds (lb) | Pounds+Ounces (lb+oz) |
| 0.1 kg | 0.220 lb | 0 lb 3.527 oz |
| 1 kg | 2.205 lb | 2 lb 3.274 oz |
| 5 kg | 11.023 lb | 11 lb 0.370 oz |
| 10 kg | 22.046 lb | 22 lb 0.740 oz |
Reservation
In some cases, there is a slight swelling at the injection site, it disappears after 2-3 days without special treatment.
After the last application of the drug slaughter of animals for meat is allowed in 28 days, people can eat milk in 14 days. Meat obtained earlier than this period is used only for feeding carnivores and making meat and bone meal, milk – fed to unproductive animals.
Storage conditions
In a dry dark place, out of reach of children at a temperature of +5 to +25 ° C.
Expiration date
2 years.
