Florfenicol 100 mg/ml ORAL Solution (RESFLOR, Nuflor, Norfenicol, Florvio, Aquaflor analog), 100 ml

Florfenicol for poultry and pigs

1 ml of the drug contains:

florfenicol – 100 mg

Description

The liquid is light yellow, transparent.

Pharmacological properties

Florfenicol is a derivative of thiamphenicol, where the hydroxyl group is substituted by a fluorine atom. Active against acetyltransferase-producing pathogens and resistant to chloramphenicol, it provides bacteriostatic and bactericidal action by binding in the protoplasm of the bacterial cell to the ribosomal subunit of 70S bacteria, blocking the enzyme peptidyltransferase, which leads to disruption of transport microorganisms.

After oral administration, the bioavailability of florfenicol is: in pigs – 88%, in poultry – at least 55%. High levels of antibiotic concentrations are observed in the lungs, kidneys, muscles, intestines, heart, liver, spleen, and serum. The maximum concentration in the blood is reached after 1 hour, the therapeutic concentration is maintained in the organs and tissues of pigs and poultry for 24 hours. It is excreted unchanged and as metabolites: in poultry mainly in the feces, in pigs – in the urine and partly in the feces.

Indication

Treatment of animals with diseases caused by gram-positive and gram-negative microorganisms – Staphylococcus spp., Streptococcus spp., Proteus spr., Salmonella spr., Escherichia coli, Actinobacillus pleuropneumoniae, Ornitobacterium rhinotrachela, Bronchile sphele, Pasteurella, Pasteurella. , Klebsiella spp., Campylobacter spp., Enterobacter spr., Aeromonas spr., Flexibacter spr., Chlamydia spp. etc., mycoplasma M. hyopneumoniae, M. hyorhinis:

• poultry (broiler chickens, breeding chickens, repair young, turkeys) – colibacillosis, staphylococcal infection, pasteurellosis, respiratory and gastrointestinal diseases;
• pigs – hemophilic and actinobacillary pleuropneumonia, atrophic rhinitis, Glaser’s disease (hemophilic polyserositis), pasteurellosis, diplococcal septicemia, streptococcal and staphylococcal infections, mycoplasmosis, secondary infection with viral pathology and other diseases.
• APPLICATION

  Method of application and dosage

  The drug is administered orally with drinking water in the following doses:

  • broiler chickens, breeding chickens, repair young stock, turkeys – 0.2 ml per 1 kg of body weight or 1 ml per 1 liter of drinking water;
  • chickens, turkeys older than 1 month – 2 ml per 1 liter of drinking water daily, the course – 3 days, in severe cases and salmonellosis – 5 days;
  • pigs – 1-1.5 ml per 10 kg of body weight or 1 ml per 1 liter of drinking water, the course – 5-7 days.

  During treatment, animals should drink only water with the drug.

   

  *Kilograms to a Pounds conversion table

  Kilograms (kg)	Pounds (lb)	Pounds+Ounces (lb+oz)
  0.1 kg	0.220 lb	0 lb 3.527 oz
  1 kg	2.205 lb	2 lb 3.274 oz
  5 kg	11.023 lb	11 lb 0.370 oz
  10 kg	22.046 lb	22 lb 0.740 oz

  Reservation

  After the last application of the drug, slaughter of pigs for meat is allowed in 1 day, poultry – in 2 days. Meat obtained before this date is disposed of or fed to unproductive animals, depending on the conclusion of the veterinarian.

Contraindication

Do not use in animals with hypersensitivity to florfenicol, sows during pregnancy and lactation, breeding boars, laying hens, the eggs of which are eaten by humans. Do not use concomitantly with thiamphenicol and chloramphenicol.

Storage conditions

In a dry, dark place, out of reach of children at a temperature of +5 to +25 ° C.

After opening the vial, use the drug for 14 days, aqueous solution of the drug – for 24 hours.

Expiration date

2 years.