PRAZIMEC – C® (praziquantel, abamectin) Tablets for cats, 12 tablets

COMPOSITION

One tablet (60 mg) contains the active substances:

praziquantel – 6.25 mg

abamectin – 0.25 mg

PHARMACOLOGICAL ACTION
Praziquantel induces antihelminitic effect (anticestodal and to certain extent also antitrematodal).
It exerts an anticestodal action against some cestodes (tapeworms) which inhabit mainly the
digestive tract of cats – Diphyllobothrium latum, Dipylidium caninum (sexually mature forms),
Spirometra erinacei europei, Mesocestoides lineatus, Hydatigera taeniaeformis, Taenia
hydatigena, as well as antitrematodal action against trematodes (flukes) – Opisthorchis felineus,
Alaria alata. Abamectin is an endectocide, which affects both internal and external parasites
– it induces anthelmintic (antinematodal) and antiarthropodal effect (insecticidal and acaricidal
against parasitizing insects and ticks) in cats. Its antinematodal effect is directed against
roundworms, and the antiarthropodal – against blood and fluid sucking insects – Ctenocephalides
cati (feline flea), C. canis (canine flea), Pulex irritans (human flea), Dipelatonema reconditum,
Felicola subrostratus (cat lice), and ticks – Notoedres cati, Otodectes cynotis, Cheyletiella blakei,
Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus, etc. The effect of praziquantel
is based on suppression of fumarate reductase in the myofibril membranes and neuro-muscular
synapses, as a result of which paralysis and death of helminths occur. Abamectin stimulates the
release of gamma-aminobutyric acid (GABA), hindering the transmission of nerve impulses,
which causes paralysis of nematodes, insects and ticks. The two active substances of the
preparation complement each other’s action, thereby providing a wider antiparasitic effect.
Indications
In infestation of cats with endoparasites tapeworms (teniae), flukes, roundworms (nematodes);
with ectoparasites – lice, fleas, pasture ticks, notedric mange (feline scabies), “walking” dandruff
(cheyletiellosis) and other mange, and particularly in cases of complex endo- and ectoparasitic
invasion.

Contraindications
Do not administer to pregnant cats, to sucking kittens and to kittens below two months of age.
MODE OF ADMINISTRATION
Orally, with non-liquid feed.
TARGET SPECIES
Cats.
PRAZIMEC – C® Tablets for cats (praziquantel, abamectin)
DOSAGE
In endoparasitosis – 1 tablet per 2.5 kg b.w.
In ectoparasitosis – 2 tablets per 2.5 kg b.w.
The treatment may be repeated after 7-10 days (mainly in ectoparasites).
In cases of flea infestation, the living premises must be obligatorily disinfected.

SIDE EFFECTS
Not established.
STORAGE
In the original packing, well-closed, in dry and well-ventilated facilities, protected from direct
sunlight.
PACKING
3 boxes of 4 tablets each
WARNING
Keep out of the reach of children!