Simparica Chewable for Dogs  40-60 kg (88-132lbs) (3tab) ?3 Month Supply

Description:

Tablets for oral administration of a square shape with an inscription on one side: “5” (dosage 5 mg / tab.), “10” (dosage 10 mg / tab.), “20” (dosage 20 mg / tab.), “40 “(Dosage 40 mg / tab.),” 80 “(dosage 80 mg / tab.) Or” 120 “(dosage 120 mg / tab.), With rounded corners, brown speckled.

Structure:

1 tablet contains sarolaner – 5 mg, 10 mg, 20 mg, 40 mg, 80 mg or 120 mg, depending on the dosage, as well as auxiliary substances: lactose monohydrate, sodium carboxymethyl starch, colloidal silicon dioxide, magnesium stearate and a flavoring granular base …

Pharmacological properties:

Simparica belongs to the group of insectoacaricidal preparations of systemic action.

Sarolaner, which is part of the drug, is a compound of the isoxazoline group, which is active against fleas, ixodid, sarcoptoid, psoroptoid and demodectic ticks parasitizing dogs. Sarolaner acts at the neuromuscular synapses of arthropods and inhibits the function of the neurotransmitter receptor, gamma-aminobutyric acid (GABA) and glutamate receptor, causing uncontrolled neuromuscular activity leading to the death of insects and ticks.

Sarolaner is active against adult fleas (Ctenocephalides canis, C. felis), some species of ticks (Dermacentor reticulatus, Ixodes hexagonus, I. ricinus, Rhipicephalus sanguineus and Sarcoptes scabiei). Laboratory studies have shown the activity of sarolaner against tick species such as Dermacentor variabilis, Ixodes scapularis, Amblyomma americanum, A. maculatum, as well as the Demodex canis and Otodectes cynotis ticks.

After application of the drug, sarolaner is active against fleas after 8 hours, and against ticks (Ixodes ricinus), the effect of the drug begins after 12 hours and lasts for 28 days after application. The drug acts on all types of fleas that parasitize dogs, causes their death before the eggs are laid, and prevents flea eggs from contaminating the habitats of animals affected by fleas.

Doses and method of administration:

The drug is administered to dogs once orally with or without food at a dose of 2-4 mg / kg of animal body weight:

• 5 mg – one tablet for dogs weighing 1.3-2.5 kg;
• 10 mg – one tablet for dogs weighing 2.5 – 5 kg;
• 20 mg – one tablet for dogs weighing 5-10 kg;
• 40 mg – one tablet for dogs weighing 10 – 20 kg;
• 80 mg – one tablet for dogs weighing 20-40 kg;
• 120 mg – one tablet for dogs weighing 40-60 kg.

Animals use the drug without problems, as it tastes like liver. If the dog does not eat the tablet itself, give it with food. Dividing the tablet is not allowed. In the treatment of tick-borne and flea infestations, the drug is applied to dogs once a month during the season of tick and flea activity, in accordance with the epizootic situation. In the treatment of sarcoptic mange, the drug is used in dogs once a month for 2 months. In the treatment of demodicosis, the drug is used in dogs once a month for 3 months.

Release form:

Blisters of 1, 3 or 6 tablets. Blisters are packed in cardboard boxes. Each box contains instructions for use.

Storage conditions:

Dry, dark, inaccessible to children, place at a temperature of 15 to 25 ° C.

Shelf life:

30 months.