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For a short novocaine blockade of nerves, the udder (according to Logvin) in the supraveolar space
the affected quarter is injected with 150-200 ml of a 0.5% solution of novocaine.
For blockade of the external sacral nerve (according to Bashkirov) in loose fiber between the large and small
80-100 ml of 0.5% novocaine solution are injected with the lumbar muscles of the corresponding side.
For paranephral blockade (according to Vishnevsky), the drug is injected into the perinephric tissue.
Doses and methods of administration of the drug depend on the purpose of use (possible infiltration of the solution into
tissue, to the place of passage of the nerve, intravenously or intraarterially). It is also possible to use
drug as a solvent for dry forms of antibiotics.
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Sulfaguanidine antimicrobial.
Competitively blocks the sorption of PABA and prevents its inclusion in the dihydrofolic acid molecule (inhibits dihydropteroate synthetase), decreases the formation of tetrahydrofolic acid, and then the synthesis of purine and pyrimidine bases, nucleic acids.
When ingested, it is mainly retained in the intestines (absorbed slightly), where a high bacteriostatic concentration is gradually created. Inhibits the growth of Escherichia coli and reduces the synthesis in the intestine of thiamine, riboflavin, niacin, etc.
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