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Ketofur 100 – 100 ml

$38.69

Ketofur – 100 ml. Solution for injection 

Size: 100 ml

Active ingredient: ceftiofur hydrochloride – 50.0 mg; ketoprofen – 50.0 mg.

✔ Prevention and treatment of sows, piglets, calves, lambs, minks with iron deficiency anemia

Quality Good

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Description

Ketofur 100 – 100 ml. Solution for injection

Pig treatment for respiratory diseases

Description

Vials closed with rubber stoppers for aluminum running in 100 ml

The oily suspension from yellow to brownish-yellow in color, with a slight smell of constituents, exfoliates during storage.

Composition

1 ml of the drug contains active ingredients:

ceftiofur hydrochloride – 50.0 mg;

ketoprofen – 50.0 mg.

ATC vet classification code QJ01- antibacterial veterinary preparations for systemic use. QJ0DD99 – ceftiofur, combinations.

Ceftiofur belongs to the group of third-generation cephalosporins. It is active against gram-positive and gram-negative bacteria, including strains producing beta-lactamases, and some anaerobic bacteria: Escherichia coli, Pasteurella haemolytica, Pasteurella multocida, Haemophilus Somnus, Actinobacillus pleuropneumoniae, Haemophilus parasuisocismellis, Salisuochemella parasuisis, Salisemis paraphuisis, Salis hemophilis paraleguis, Salmonis parasiusis, Pleisuoccephis Vulgaris, , Staphylococcus spp., Actynomyces pyogenes, Salmonella typhimurium, Streptococcus agalactiae, S. dysgalactiae, S. bovis, Klebsiella spp., Citrobacter spp., Enterobacter spp., Bacillus spp., Proteus spp., Poromomeromomium fungomomerumoma bomomerumomacteromumum ) The mechanism of action of the antibiotic is to suppress the synthesis of the bacterial cell wall.

Ketoprofen – NSAIDs based on propionic acid. It has analgesic, anti-inflammatory and antipyretic effects. The mechanism of action is associated with inhibition of prostaglandin synthesis at the level of cyclooxygenase. In addition, ketoprofen inhibits lipoxygenase, has anti-bradykinin activity, stabilizes lysosomal membranes, and causes a significant inhibition of neutrophil activity. Ketoprofen is a dual inhibitor of inflammation, blocking the action of cyclooxygenase and lipoxygenase and, thus, preventing the formation of prostaglandins and leukotrienes.

Ketoprofen is a painkiller that affects the central and peripheral nervous systems. Its effect is the direct suppression of the action of bradykinin, vasodilators and pain mediators.

After parenteral administration, ceftiofur is rapidly absorbed into the injection site and penetrates into all tissues of the animal. Its maximum plasma concentration is observed after an hour, which is maintained at a therapeutic level for up to 24 hours, depending on the type of animal.

Ceftiofur in the body is rapidly metabolized to form desfuroilceftiofur, which has activity equivalent to ceftiofur against bacteria. This active metabolite binds back to plasma proteins and accumulates in the focus of infection, while its activity does not decrease in the presence of necrotic tissues.

Withdrawal of the antibiotic occurs mainly with urine and feces.

Ketoprofen is rapidly absorbed. Binds to plasma proteins. Significant concentrations of ketoprofen were found in the synovial fluid, and its level is higher than in plasma, and the half-life is 2-3 times higher than in plasma. Ketoprofen is metabolized in the liver to minor biologically active metabolites, and 90% is excreted in the urine as glucuronide compounds.

Application

Treatment of pigs with respiratory diseases caused by microorganisms (Haemophilus Somnus, Actinobacillus pleuropneumoniae, Salmonella cholerasuis and Streptococcus suis), sensitive to ceftiofur, as well as with the complex treatment of pigs with MMA syndrome (metritis-mastitis agalactia), conditions and chronic conditions inflammatory processes of the musculoskeletal system.

Dosage

Intramuscularly once a day at a dose of 1 ml per 16 kg of animal body weight (3 mg of ceftiofur and 3 mg of ketoprofen per 1 kg of animal body weight) for 3 days.

Before use, the drug bottle should be shaken and heated to 36 ° C.

for Prophylactic doses:

– Piglets 3-4 – days of age – 1.5-2 ml once;

– Calves 5-6 – days of age – 8-10 ml once;

– Lambs 3-5 – days of age – 2-3 ml once;

– Mink – 0.3-0.5 ml once;

– Sows – 10 ml once 3-4 weeks before farrowing.

With the purpose of treatment, the drug is injected 2 times with an interval of 7 days in the same doses.

Contraindications

Slaughter of animals for meat is allowed 12 days after the last use of the drug. Received, before the specified time, the meat is disposed of or fed to unproductive animals, depending on the conclusion of the doctor of veterinary medicine.

Do not use in animals with hypersensitivity to active substances or to any excipient. Do not mix the drug with other drugs in the same syringe.

Precautions

Do not use in animals with acute renal failure.

Do not use in animals under 6 weeks of age.

Do not use in animals with impaired hematopoiesis, gastrointestinal ulcers, kidney, and liver diseases. Do not use in animals in a state of hypotension, hypovolemia, and dehydration.

Do not use simultaneously with other non-steroidal anti-inflammatory, diuretics, or anticoagulants, as well as with tetracyclines, chloramphenicol, macrolides, and lincosamides.

Form of packaging

Glass bottles 100 ml, 200 ml closed with a rubber plug under an aluminum cap.

Storage

Dry dark place at a temperature from 10 ° C to 25 ° C. Avoids freezing.

Expiration date – 3 years from the manufacturing date.

✔ Please note there is in stock ➫ Piperahelm 450 ProLevamisoleIvermectin

Additional information

Active substances

,

Dosage form

injection

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