The active substance of the medicine is ivermectin and belongs to composites, which are produced by microorganisms of Streptomyces avermitilis group. The medicine has a pronounced activity against endo- and ectoparasites of animals and poultry. The mechanism of the medicine action on the parasite’s body is in the stimulation of the allocation of a neurotransmitter the gamma-aminobutyric acid inhibition (GABA). As a result, there is a blockade of impulse transfer between the interneurons and the motor excitatory neurons of the parietal abdominal trunk, which leads to its paralysis and death.
Application Cattle, sheep, goats, pigs, rabbits: prevention and treatment of diseases, caused by gastrointestinal and pulmonary nematodes, subcutaneous, nasopharyngeal, gastric vessels (in the larvae phase), scabies, lice, hairworms.
For the treatment of chronic, subacute and acute forms of fasciolosis in cattle and small ruminants (sheep and goats). The drug affects all stages of Fasciola hepatica and F. gigantica and active against most species of related nematodes and cestodes. The drug can be used for the treatment of mixed trematode (fluke) and nematode due to gastrointestinal roundworms, lungworms, liver fluke.
albendazole – methyl [5-(propilsulfanil)-1n-benzimidazole-2-il] carbamate belongs to the group of benzimidazole. Albendazole exhibits larvicidal, ovicidal and vermicidal activity, and is thought to exert its anthelmintic effect by inhibiting tubulin polymerization. This causes a cascade of metabolism disruption, including energy depletion, which immobilizes then kills the susceptible helminth.
Albendazole – broad-spectrum anthelmintics, effective on mature forms of trematodes (Fasciola hepatica and Dicrocоelium lanceatum), nematodes, that parasitize in the digestive tract and lungs (Bunostomum spp., Cooperia spp., Dictyocaulidae spp., Haemonchus spp., Nematodirus spp., Ostertagia spp., Strongyloides spp., Triсhostrongylus spp., Trichuris spp. etc.), and some species of cestodes (Avitellina centripumctata, Moniezia expansa, Moniezia benedeni, Thysaniezia giardi).
APPLICATION. Deworming of cattle, sheep, goats, horses, pigs, dogs, cats, furry animals, birds with nematodes lesions (mature and immature forms), some types of cestodes and trematodes.