1 g of the drug contains:

benzathine benzylpenicillin – 500 thousand IU

sodium benzylpenicillin – 300 thousand IU

procaine-benzylpenicillin – 200 thousand IU

Description

White or light yellow powder.

Pharmacological properties

The drug belongs to the group of penicillins, prevents the formation of peptide bonds by inhibiting the activity of transpeptidase, disrupts the late stages of synthesis of peptidoglycan cell membrane, which leads to lysis of dividing cells.

Due to the balanced ratio of salts and auxiliary components that provide an acidic environment at the injection site, the drug has a wider range of bactericidal action. Effective against gram-positive – Staphylococcus spp., Streptococcus spp., Clostridium spp., Corynebacterium diphtheriae, Bacillus anthracis, some gram-negative microorganisms, spirochetes Borrelia, Leptospira, Treponema, most actinomycetes and other Actinomycetes.

A significant concentration of the drug in the blood is provided in the first hour after intramuscular administration and persists for at least 72 hours. The drug is excreted in the urine and bile.

Indication

Treatment of cattle, horses, pigs, sheep, goats, rabbits, dogs, cats, fur animals (foxes, foxes, minks), poultry (broiler chickens) for actinomycosis, erysipelas, necrobacteriosis, pasteurellosis, streptococcus, staphylococcosis, septicemia , pneumonia, mastitis, endometritis, abscesses, phlegmons, which are caused by microorganisms sensitive to penicillins.

Method of application and dosage

The suspension for injection is prepared aseptically, immediately before use, by adding to the vial with the drug or sterile water for injection, or isotonic sodium chloride solution in a ratio of 3 ml of solution per 1 g of the drug. After vigorous shaking, the resulting suspension is administered deep intramuscularly. In large animals, the contents of each vial are injected into different parts of the body.

Doses of the drug for different species of animals are listed in the table.

Reservation

After the last application of the drug, slaughter of animals and poultry for meat is allowed in 15 days, people can eat milk in 7 days. Meat obtained before this date is disposed of or fed to non-productive animals, milk is disposed of or fed to non-productive animals, depending on the conclusion of the veterinarian.

Contraindication

Do not prescribe to animals with hypersensitivity to the active substances of the drug and at the same time with products containing antibiotics from the group of macrolides (erythromycin, tylosin, etc.) and tetracycline, which are antagonists.

Storage conditions

In a dry, dark place, out of reach of children at a temperature of +4 to +20 ° C.

Expiration date

3 years.