Frontline for Cats
Drops Boehringer Ingelheim Frontline ComboSpot on from fleas and ticks for cats
Boehringer Ingelheim Front Line Combo Spot On.
Frontline Combo is a medicinal insectoacaricidal preparation in the form of a solution for external use. Frontline Combo contains fipronil-9.8% and S-methoprene-8.8% as active ingredients, and polyvidone and polysorbate as auxiliary substances. Frontline Combo is a colorless transparent liquid with a slight specific odor.
Frontline Combo is produced in packs of 0.5; 0.67; 1.34; 2.68 and 4.02 ml into polyethylene pipettes with a break-off tip, which indicate the name of the manufacturer, the name and amount of the drug, batch number, date of manufacture.
Store Frontline Combo as a precaution (list B) in the manufacturer’s packaging, in a dry, dark place at a temperature from 0C0 to 25C0. The shelf life of Frontline Combo, subject to storage conditions, is 3 years from the date of manufacture. Front Line Combo should not be applied beyond the expiration date.
Frontline Combo has a pronounced contact insectoacaricidal effect, is active against the preimaginal and imaginal phases of development of lice, fleas, lice and ticks (ixodid, cheilitella) parasitizing on dogs and cats. The mechanism of action of fipronil, which is a part of Frontline Combo, is to block the GABA-dependent (GABA-gamma-aminobutyric acid) receptors of parasites, impair the transmission of nerve impulses, which leads to paralysis and death of ectoparasites. S-methoprene inhibits the juvenile hormone that promotes the formation of chitin, thereby disrupting the development of fleas at the egg and larval stage.
When applied to the skin, the drug is not absorbed, but gradually, within 24 hours, is distributed over the surface of the body and, being reserved in the sebaceous glands, has a long-term insectoacaricidal effect in the places of localization of ectoparasites.
Frontline Combo, in terms of the degree of impact on the body, refers to low-hazard substances (hazard class 4 according to GOST 12.1.007.76), in recommended doses, it does not have skin-resorptive, sensitizing, embryotoxic, teratogenic and mutagenic effects. Causes minor irritation in eye contact.
The procedure for applying the vaccine
Frontline Combo is used to combat fleas, lice, lice and ticks (ixodid, cheilitella) of dogs and cats by topical (pipette) application to the skin. Before processing, the tip of the pipette is broken off, the animal’s hair is pushed apart in the region of the back (between the shoulder blades) and, pressing the pipette, the preparation is applied to the skin at one or several points. For the treatment of dogs weighing more than 40 kg, use a combination of pipettes of different volumes.
The protective effect of the drug against ixodid ticks in cats lasts up to 3 weeks, against the imago and preimaginal phases of insect development up to 6 weeks. The protective effect of the drug against ixodid ticks in dogs lasts for at least 1 month, against adult insects for up to 3 months, from the preimaginal phases of insect development up to 8 months. In case of severe damage to the animal by lice, fleas, lice, it is recommended to process it once a month. If the animal is washed more than 2 times a month, it is recommended to reduce the interval between treatments to 3 weeks. It is not recommended to wash animals within 48 hours after treatment with Frontline Combo, as well as to use other insecticidal acaricides. There were no side effects and complications in animals when using Frontline Combo according to the instructions for use. In case of increased individual sensitivity to the components of the drug and the appearance of signs of allergic reactions, the treatment is stopped, the drug is washed off with water, and antihistamines are given inside. Sick and recovering animals, as well as puppies and kittens younger than 8 weeks of age, cannot be processed.
Personal prevention measures
When working with Front Line Combo, you should follow the rules of personal hygiene and safety measures provided for working with medicinal products for animals.
While working with the medicinal product, it is not allowed to drink, smoke, eat.
In case of accidental contact with Front Line Combo on the skin or mucous membranes, it should be washed off with a stream of water. At the end of work, hands should be washed with warm water and soap.
It is forbidden to use empty pipettes from under the drug for domestic purposes, they must be disposed of with household waste.
Front Line Combo should be kept out of the reach of children.
Manufacturer: Boehringer Ingelheim