Firmaks 50 mg for dogs 5 – 10 kg / 11 -22 lbs (firocoxib, previcox analog), 20 tablets

Description

Round tablets are biconvex yellowish-white.

Storage

The drug is designed for dogs with different body weights; each tablet contains the active substance at the rate of 5 mg of firocoxib per 1 kg of body weight of the animal.

Excipients: lactose monohydrate, microcrystalline cellulose, calcium stearate, polyvinylpyrrolidone, corn starch, colloidal silicon dioxide, yeast powder.

Pharmacological properties

ATCvet QМ01АН90, non-steroidal anti-inflammatory and anti-rheumatic drugs.

FIROMAX is a non-steroidal anti-inflammatory drug based on firocoxib, which is a selective inhibitor of COX-2 (cyclooxygenase-2). The mechanism of action of firocoxib is a selective violation of the formation of prostaglandins involved in the formation of the inflammatory response, and suppression of the proliferative and exudative phases of inflammation. It mainly acts in the focus of inflammation and has a very weak effect on the production of prostaglandins, which regulate renal blood circulation and the integrity of the gastrointestinal tract. Has anti-inflammatory, analgesic and antipyretic effects.

The maximum concentration of firocoxib in the blood plasma of dogs is reached after 1.25 (± 0.85) hours, the bioavailability is 36.9 (± 20.4)%. The maximum concentration of the active substance in blood plasma is 0.52 (± 0.22) μg / ml. The half-life is 7.59 (± 1.53) hours.

Firocoxib is completely bound to blood proteins, metabolized in the liver and excreted in the bile through the gastrointestinal tract.

Application

To reduce inflammation and pain in the treatment of dogs with osteoarthritis; as an anti-inflammatory, analgesic and antipyretic in the perioperative period (orthopedic, dental and soft tissue surgery).

Dosage

The drug is administered to dogs individually once orally with food or forcibly at the root of the tongue in the minimum therapeutic dose: 5 mg of firocoxib per 1 kg of body weight per day once.

Depending on the weight of the dog, the actual dosage is:

For dogs weighing more than 45 kg, the drug can be dosed with a suitable combination of tablets

Adherence to a diet or special feeding regime is not required. Separation of the tablet is not allowed.

*Kilograms to a Pounds conversion table

Osteoarthritis:

The duration of the drug depends on the condition of the animal and is determined by a veterinarian.

Long-term treatment (more than 90 days) should be performed with caution and under the constant supervision of a veterinarian.

Surgical interventions:

To reduce pain, the drug is used 2 hours before surgery. If necessary, treatment is continued for 3 days. Treatment of dogs after orthopedic surgery may take longer, as determined by a veterinarian.

Contraindication

Do not use in animals with hypersensitivity to the active substance or other components of the drug!

Do not use in pregnant or lactating animals!

Do not use in dogs under 10 weeks of age and / or weighing less than 3 kg!

Do not use in animals with possible gastrointestinal bleeding, blood dyscrasias or haemorrhagic disorders!

Do not use concomitantly with other nonsteroidal anti-inflammatory drugs or corticosteroids!

Reservation

When using the drug strictly adhere to the recommended dosage.

The use of the drug in very young animals and animals with suspected or confirmed liver, heart and kidney dysfunction may be an additional risk.

In this case, the drug should be used if necessary and under the supervision of a veterinarian.

Do not use in dehydrated and hypovolaemic or hypotensive animals due to the risk of increased nephrotoxicity.

Concomitant use with agents that are toxic to the kidneys should be avoided.

Animals at risk of gastrointestinal bleeding or previously hypersensitive to NSAIDs should only be used under the supervision of a veterinarian.

Prior to and periodically during the use of the drug, it is recommended to conduct appropriate laboratory tests to determine the basic biochemical parameters of the kidneys or liver.

The drug should be discontinued immediately if any of the following symptoms are observed: vomiting, diarrhea, faecal occult blood, loss of appetite, sudden weight loss, lethargy, deterioration of renal or hepatic biochemical parameters.

Release form

Polymer vials with polypropylene lids of 20 tablets, packed individually in cardboard boxes.

Storage

The drug is stored in the original packaging of the manufacturer, separately from food and feed, in a dry place, protected from direct sunlight, out of reach of children and animals at a temperature of 0 to 30 ° C.

Expiration date

3 years.

For use in veterinary medicine!