Ultrasept (sulfadimine, oxytetracycline, trimethoprim, tylosin, norsulfazole)

Description
Cylindrical tablets with a flat surface, the line and beveled, from light yellow to yellow (on the surface of tablets allowed marbling-inclusions).

Composition
1 tablet (0.8 g product) contains the active ingredients:
sulfadimine – 70 mg;
oxytetracycline hydrochloride – 45 mg;
trimethoprim – 30 mg;
tylosin tartrate – 25 mg;
norsulfazole – 80 mg.

Pharmacological properties
Ultraseptol pills – a comprehensive drug broad spectrum bactericidal and bacteriostatic action.

Sulfadimine – sulfonamides, active against gram-positive and gram-negative bacteria: E. coli, Shigella spp., Klebsiella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii. The mechanism of action is associated with inhibition of PABA and competitive dyhidropteroatsyntetazy, leading to disruption of the synthesis tetrahidrofoliyevoyi acid needed for the synthesis of purines and pyrimidines.

Oxytetracycline – bacteriostatic antibiotic mechanism of action of which is to initiate protein synthesis during its interaction with ribosomes, as well as to reduce the permeability of the cytoplasmic membrane of sensitive microorganisms. The drug has a wide range of effects on gram-positive and gram-negative microorganisms: Streptococcus spp., Clostridium spp., Corynebacterium spp., Brucella spp., Haemophilus spp., E. coli, Pasteurella spp., Klebsiella spp., Erysipelothrix spp., Fusobacterium spp. , Salmonella spp., as well as the simplest (Protozoa), mycoplasma (Mycoplasma spp.), rickettsia (Rickettsia spp.) and chlamydia (Chlamydia).

Tylosin – a mixture of macrolide antibiotics produced by a strain of Streptomyces fradiae, comprising mainly tylosin A. tylosin is effective against gram-positive and some gram-negative microorganisms: Corynebacterium spp., Clostridium spp., Erysipelothrix spp., Pasteurella spp., Vibrio spp., Leptospira spp., Brucella spp., Neisseria spp., Haemophilus spp., and against rickettsiae (Rickettsia spp.), spirochetes (Spirochaetes (Borrelia anserina, Brachyspira hyodysenteriae)), mycoplasma (M. gallisepticum, M. synoviae, M. meleagridis, etc..). Tylosin exhibits bacteriostatic effect by inhibition of protein synthesis (via irreversible connection with bacterial 50S ribosomal subunits) and microbial cell growth and reproduction, respectively.

Norsulfazole – bacteriostatic antimicrobial agent, active in relation to hrampopozytyvnyh and gram-negative microorganisms: Escherichia coli, Shigella spp., Klebsiella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Usege

Calves under 3 months: treatment of animals suffering from gastroenteritis, salmonellosis, pasteurellosis, campylobacteriosis (vibriosis), digestive disorders with clinical signs of diarrhea caused by pathogens susceptible to the components of the preparation.

Pigs: Treatment of animals suffering from enzootic pneumonia, arthritis, dysentery, edema disease, erysipelas, salmonellosis, pasteurellosis, caused by microorganisms sensitive to components of the drug.

Lambs under 3 months: treatment of animals suffering from eymerioz, septicemia, contagious agalactia, caused by microorganisms sensitive to components of the drug.

Rabbits: the treatment of animals suffering from coccidiosis, pasteurellosis, salmonellosis, septicemia caused by pathogens susceptible to the components of the drug.

Poultry (chickens (broilers), turkeys, geese, ducks): treatment of birds suffering from coccidiosis, typhoid, cholera, salmonellosis, mycoplasmosis, rhinitis, caused by microorganisms sensitive to components of the drug.

Dosage

Oral with dry or wet food individually or by group, after crushing the pills.

The daily dose for all species is 0.8-1.2 g (1-1.5 tablets) per 10 kg body weight, which is given in two divided doses. The first application of dose may be increased to twice (depending on severity).

Course of treatment 3-5 days (to complete disappearance of clinical symptoms). At relapse of disease treatment is carried out at least three days before the full recovery of animals. When eymeriozi treatment is 2-3 courses with an interval of 5-7 days between them.

A mixture of feed fed to the animals with the drug during the day.

Contraindications

Do not administer to animals with hypersensitivity to the active ingredients of the drug, as well as liver and kidney. Do not use ruminants functionally developed peredshlunkamy and chickens, hens, eggs are used as food for people.

Warning

Slaughter of animals and poultry for meat is allowed after 8 days after the last administration of the drug. Received, by the deadline, meat or dispose of unproductive animals are fed, according to a doctor of veterinary medicine.

Storage

Dry, dark, place inaccessible to children at temperature from 4 °C to 25 °C.

Do not store together with food, beverages and animal feeds.

Shelf life – 2 years from date of manufacture.