Megestrol acetate 5.0 mg.

Animal VetLine AntiSex tablets for dogs and cats (packaging)

Release form

5 blisters of 10 tablets, blisters are packed in cardboard boxes.

Application

The drug has antiestrogenic and antiovulatory effects, is used to delay or interrupt estrus in bitches and cats, without negatively affecting subsequent pregnancies. In males and cats, the drug inhibits sexual activity and regulates their behavior.

Description

Tablet from white to cream color with a specific odor.

Composition

490mg of the drug contains the active ingredient:

megestrol acetate – 5.0 mg.

Excipients: lactose, calcium stearate, powdered sugar, starch, flavor.

Pharmacological properties

АТСvet QG03, hormones of the gonads and veterinary drugs used in the pathology of the genital area (QG03AC05, megestrol)

The active ingredient of the drug is a synthetic progestogen – megestrol acetate, a highly effective synthetic progesterone-like hormone. It acts on the hypothalamic-pituitary system, blocks the secretion of gonadotropic hormones of the adenohypophysis. A decrease in the level of gonadotropic hormones (FSH and LH) in the blood leads to a violation of folliculogenesis in females and testosterone synthesis in Leydig cells in males, as a result of which there is a suppression of sexual desire in animals.

When using the drug before the onset of estrus, females observe inhibition of the secretion of gonadotropic hormones and prevent ovulation. If the drug is used at the beginning of the follicular phase (second or third day of estrus), it leads to the interruption of estrus.

Megestrol acetate has the same effect as other progestogen drugs. Has significant antiestrogenic and antiglucocorticoid activity.

The drug is well absorbed from the gastrointestinal tract, metabolized in the liver, and excreted from the body.

Dosage

Orally with food or forced directly onto the root of the tongue:

for cats:

For sedation with sexual arousal – 1 tablet daily for 3 – 5 days.

cats:

To prevent estrus – 1 tablet for 10-14 days. After discontinuation of the drug, estrus occurs after 14 days;
To stop estrus – 1 tablet daily for 3 to 5 days (from the moment signs of sexual arousal appear)
As a contraceptive – 3 tablets within 24 hours after mating.

bitches:

To prevent estrus – 1 tablet per 10 kg of animal body weight once every 14 days. After discontinuation of the drug, estrus occurs after 21 days
To stop estrus – 1 tablet per 10 kg of the animal’s body weight for 7 days (from the moment signs of sexual arousal appear).
As a contraceptive – 2 tablets per 5 kg of body weight of an animal daily for 2 days after mating.

males:

For sedation with sexual arousal – 1 tablet per 10 kg of animal body weight daily for 5 days.

Contraindications

The drug is not recommended for use in animals with diseases of the reproductive system (pyometra, metritis, endometritis), breast tumors, diabetes, immature animals, pregnant and lactating animals.

It is not recommended for young females before the first estrus or as anesthetic therapy for violations of the sexual cycle.

Warning

With prolonged use of the drug, changes in the reproductive cycle, an increase in the mammary glands, excessive appetite, and an increase in the weight of the animal are possible.

Release form

5 blisters of 10 tablets, blisters are packed in cardboard boxes.

Storage

Store the drug in a dry, dark place out of the reach of children and animals, separately from food and feed at a temperature of 4 to 25 0С.

Shelf life 3 years.

For use in veterinary medicine!

Manufacturer: Animall