Dectomax (doramectin) Injection for Cattle and Sheep

Description:
A medicinal product in the form of a solution for injection, intended for the treatment and prevention of nematodes and arachnoentomoses in cattle, sheep, goats and pigs.

In appearance it is a sterile solution, colorless or pale yellow in color.

Composition:
1 ml of the drug contains 10 mg of doramectin as an active ingredient; as auxiliary substances – ethyl oleate, butylhydroxyanisole, sesame oil.

Pharmacological properties:
Dectomax is a ready-to-use sterile pale yellow or colorless solution containing 1% doramectin (10 mg / ml). Doramectin is a new member of the avermectin group. The drug modulates the activity of chloride channels in cell membranes in the nervous system and muscles of nematodes and arthropods. By binding to receptors, it increases the permeability of membranes for chlorine ions, which leads to blockade of electrical activity of nerve and muscle cells of nematodes and arthropods and their paralysis and death. In mammals, these receptors are localized only in the central nervous system, and doramectin practically does not penetrate the blood-brain barrier, therefore, in recommended doses, the drug is safe for mammals.

Indications for use:
The drug is prescribed to cattle for diseases caused by the following pathogens:

pulmonary nematodes (larvae and sexually mature forms) – Diсtyocaulus viviparus;
subcutaneous nematodes – Parafilaria bovicola;
lacrimal duct nematodes – Thelazia spp .;
lice – Linognathus vituli, Haematopinus eurystemus, Solenopotes capillatus;
larvae of nasopharyngeal and subcutaneous gadflies – Hypoderma lineatum, Dermatobia hominis, Hypoderma bovis;
parasitic stages – Chrysomyia bezziani and Cochliomyia hominovorax;
ixodid ticks – Boophilus microplus and Ornithodoros spp .;
scabies mites – Sarcoptes scabiei, Chorioptes bovis, Psoroptes ovis and Psoroptes bovis.
In addition, the drug is used to treat diseases caused by Haematobia irritans and Damalinia bovis.
Sheep and goats Dectomax is prescribed for diseases caused by:

pulmonary helminths – Dictyocaulus filaria;
nasopharyngeal gadfly larvae – Oestrus ovis;
scabies mites – Psoroptes ovis;
nematodes of the gastrointestinal tract – Ostertagia (Teladorsagia) circumcincta, Cooperia curticei, Nematodirus spp., Ostertagia (Teladorsagia) circumcincta, Haemonchus contortus, Trichostrongilus axei, T. Vitrinus and C. Oncophora.
In pigs, the drug is used for:

pulmonary nematodes – Metastrongylus spp .;
renal nematodes – Stephanurus dentatus;
lice and scabies mites – Haematopinus suis and Sarcoptes scabiei;
gastrointestinal nematodes.
Dosage:
The drug is administered intramuscularly or subcutaneously to cattle and sheep. Pigs only intramuscularly. It is recommended to inject Dectomax subcutaneously into the neck or shoulder of the animal, and intramuscularly into the neck muscles. The drug should be administered in compliance with the rules of asepsis, using dry sterile syringes and needles. Cattle: The dose of the drug is 0.2 mg of doramectin per 1 kilogram of live weight, which corresponds to 1 ml of Dectomax solution per 50 kg of body weight. Sheep: The dose of the drug is 0.2 mg of doramectin per 1 kg of live weight, which corresponds to 1 ml of Dectomax solution per 50 kg of body weight. Pigs: Dectomax is only administered intramuscularly at the base of the ear. Dose 0.3 mg per 1 kg of live weight (1 ml per 33 kg of body weight).

Side effects when using the drug in accordance with the instructions are not noted.

Waiting period:
The drug should not be used in animals from which milk is obtained for food purposes. In this regard, cows and sheep, from which they will receive milk for food purposes, are prohibited from using the drug later than 35 days before delivery. Slaughter of cattle and sheep for meat is allowed no earlier than 35 days after the last injection of the drug. In case of the forced slaughter of animals before the specified terms, the slaughter products can be used to feed fur-bearing animals.