Baktifur 10% Solution for injection (Excede analog), 100 ml
DESCRIPTION
Oily suspension for injection from white to light brown.
COMPOSITION
1 ml of the drug contains the active substance:
free acid of crystalline ceftiofur – 100 mg.
Excipients: cottonseed oil, medium chain triglycerides.
PHARMACOLOGICAL PROPERTIES
АТС vet classification code QJ01 – antibacterial veterinary drugs for systemic use.
Ceftiofur is a semi-synthetic third-generation cephalosporin antibiotic. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria (Pasteurella haemolytica (Mannheimia spp.), Escherichia coli, Pasteurella multocida, Haemophilus somnus, Heamophilus parasuis , Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica), Arcanobacterium pyogenes, Fusobacterium necrophorum Actinobacillus pleuropneumoniae and Streptococcus suis). Ceftiofur blocks (suppresses) the synthesis of bacterial cell walls by inhibiting the synthesis of peptidoglycan.
Ceftiofur is active against the following pathogens that cause respiratory and other infectious diseases in pigs: Actinobacillus pleuropneumoniae , Pasteurella multocida , Heamophilus parasuis and Streptococcus suis .
Following parenteral administration, ceftiofur is rapidly metabolized to desferalceftiofur, the active metabolite. Due to plasma protein binding, the active metabolite of ceftiofur is concentrated at the site of inflammation.
The maximum concentration of the antibiotic in the blood plasma is reached 22 hours after the administration of the drug. The release of the drug from the body occurs within 10 days after administration. Ceftiofur is excreted from the body mainly with urine, and also partially with feces.
INDICATIONS FOR USE
Treatment of pigs suffering from septicemia, polyarthritis, polyserositis, as well as respiratory diseases and other infectious diseases caused by microorganisms susceptible to ceftiofur.
DOSAGE AND ADMINISTRATION
Intramuscularly at a dose of 1 ml per 20 kg of body weight (5 mg of active ingredient per 1 kg of body weight) once in the neck.
Before use, the vial with the drug must be thoroughly shaken until a homogeneous suspension is obtained and the precipitate is resuspended.
The maximum volume of the drug for injection in one place should not exceed 4 ml.
*Kilograms to Pounds conversion table
| Kilograms (kg) | Pounds (lb) | Pounds+Ounces (lb+oz) |
| 0.1 kg | 0.220 lb | 0 lb 3.527 oz |
| 1 kg | 2.205 lb | 2 lb 3.274 oz |
| 5 kg | 11.023 lb | 11 lb 0.370 oz |
| 10 kg | 22.046 lb | 22 lb 0.740 oz |
CONTRAINDICATIONS
Do not administer to animals with hypersensitivity to beta-lactam antibiotics.
Do not administer intravenously.
CAUTIONS
Slaughter of animals for meat is allowed 71 days after the last use of the drug.
The meat obtained before the specified period is disposed of or fed to unproductive animals, depending on the conclusion of a veterinarian.
The use of the drug should be based on the determination of the sensitivity of pathogens, as well as taking into account official and local rules for the use of antimicrobials.
Penicillins and cephalosporins may cause hypersensitivity reactions after injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins can lead to cross-reactions with cephalosporins and vice versa. Allergic reactions to these substances can sometimes be severe.
When using the drug in accordance with the package leaflet, side effects and complications, as a rule, are not observed. In some cases, it is possible to form swelling and alopecia zones at the injection site, which disappear within 56 days after the administration of the drug.
Accidental administration to humans should be avoided. In case of accidental injection to a person, you should immediately consult a doctor, showing the package leaflet or label of the drug.
It is not recommended to work with the drug for persons with hypersensitivity to beta-lactam antibiotics.
In case of contact with skin, wash thoroughly with soap and water.
In case of contact with eyes, rinse immediately with clean water.
RELEASE FORM
Vials made of neutral glass (brands NS-1, NS-2, SPS-1), closed with rubber stoppers for aluminum run-in of 10, 20, 50, 100 and 200 ml. The secondary packaging is a cardboard box.
STORAGE
Dry dark place inaccessible to children at a temperature of 5 ° C to 25 ° C.
BEST BEFORE DATE
2 years from the date of production when stored in unopened packaging under proper storage conditions.
After the first selection from the vial, the drug must be used within 14 days, provided that it is stored in a dark place at a temperature of 0 to 8 ° C.
