Baktifur 20% Solution for injection (Excede analog), 100 ml

DESCRIPTION

Oily suspension for injection from white to light brown.

COMPOUND

1 ml of the drug contains the active substance:

Ceftiofur crystalline-free acid – 200 mg.

PHARMACOLOGICAL PROPERTIES

АТС vet classification code QJ01 – antibacterial veterinary drugs for systemic use.

Ceftiofur is a semi-synthetic third-generation cephalosporin antibiotic. It has a broad spectrum of action against gram-positive and gram-negative bacteria (Pasteurella haemolytica (Mannheimia spp.), Escherichia coli, Pasteurella multocida, Haemophilus somnus, Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica), Arcanobacterium pyogenes, Fusobacterium necrophorum pynecrophorium and Streptococcus suis). Ceftiofur blocks (suppresses) the synthesis of bacterial cell walls by inhibiting the synthesis of peptidoglycan.

Following parenteral administration, ceftiofur is rapidly metabolized to desferalceftiofur, the active metabolite. Due to plasma protein binding, the active metabolite of ceftiofur is concentrated at the site of inflammation.

The maximum concentration of the antibiotic in the blood plasma is reached 12 hours after the administration of the drug, and remains at the therapeutic level for at least 7 days. Ceftiofur is excreted from the body mainly with urine, and also partially with feces.

INDICATIONS FOR USE

Treatment of cattle with necrobacteriosis (caused by Fusobacterium necrophorum and Porphyromonas levii, Bacteroides spp., Prevotella spp.), acute form of postpartum metritis (in cases where treatment with other antimicrobials has failed), caused by Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum , as well as in respiratory diseases caused by Pasteurella haemolytica (Mannheimia spp.), Pasteurella multocida, Haemophilus somnus, sensitive to ceftiofur.

DOSAGE AND ADMINISTRATION

Cattle: once subcutaneously at a dose of 1 ml of the drug per 30 kg of body weight (6.6 mg of ceftiofur per kg of body weight) .

The maximum volume of the drug for injection into one place should not exceed  30 ml.

Before use, the vial with the drug must be thoroughly shaken until a homogeneous suspension is obtained.

CONTRAINDICATIONS

Do not administer to animals with hypersensitivity to beta-lactam antibiotics.

Do not administer intravenously.

CAUTIONS

Slaughter of animals for meat is allowed 20 days after the last use of the drug. The withdrawal period for milk is 0 days.

The meat obtained before the specified period is disposed of or fed to unproductive animals, depending on the conclusion of a veterinarian.

The use of the drug should be based on the determination of the sensitivity of pathogens, as well as taking into account official and local rules for the use of antimicrobials.

Penicillins and cephalosporins can cause hypersensitivity reactions after injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins can lead to cross-reactions with cephalosporins and vice versa. Allergic reactions to these substances can sometimes be severe.

When using the drug in accordance with the package leaflet, side effects and complications, as a rule, are not observed. In some cases, the formation of swelling is possible.

Accidental administration to humans should be avoided. In case of accidental injection to a person, you should immediately consult a doctor, showing the package leaflet or label of the drug. It is not recommended to work with the drug for persons with hypersensitivity to beta-lactam antibiotics.

In case of contact with skin, wash thoroughly with soap and water.

In case of contact with eyes, rinse immediately with clean water.

RELEASE FORM

Vials made of neutral glass (brands NS-1, NS-2, SPS-1), closed with rubber stoppers for aluminum run-in of 10, 20, 50, 100 and 200 ml. Secondary packaging – cardboard boxes.

STORAGE

Dry, dark place, inaccessible to children, at a temperature of 5 ° C to 25 ° C.

BEST BEFORE DATE

The shelf life of the drug, subject to storage conditions in a closed package, is 2 years from the date of production.

After the first selection from the vial, the drug must be used within 14 days, provided that it is stored in a dark place at a temperature of 0 to 8 ° C.