Mitex ear drops, 20 ml (Miconazole nitrate, Prednisolone acetate, Polymyxin B sulfate)
Mitex (Mitex) suspension, 20 ml – is a complex veterinary drug for the treatment of otitis media in cats and dogs. Mitex drops are a triple defense against bacteria, yeast, mites and inflammatory symptoms.
Product Benefits
- Miconazole: proven to be synergistic with Polymyxin B against gram-positive bacteria such as staphylococcus aureus. Excellent activity against Malassezia and broad spectrum antifungal.
- Ear mites: Mitex is recommended for the treatment of otodectes cynotis.
- For hygienic use in the ear. Convenient 20ml bottle fits all sizes of dogs and cats.
- Prednisolone: Effectively reduces signs of inflammation such as erythema, swelling and pain, as well as itching.
- Polymyxin B: excellent activity against most gram-negative bacteria such as Pseudomonas.
- Easy to dose.
- Slim nozzle for easy application in the external ear canal.
- Approved for the treatment of localized skin infections.
- 20 ml is the optimal amount for one treatment cycle.
Composition
- Miconazole nitrate 23.0 mg / ml (equivalent to 19.98 mg miconazole)
- Prednisolone acetate 5.0 mg / ml (equivalent to 4.48 mg prednisolone)
- Polymyxin B sulfate 0.5293 mg / ml (equivalent to 5500 IU polymyxin B sulfate)
Pharmaceutical form
Ear drops and skin suspension.
Pharmacological group
Otologic drugs, corticosteroids and anti-infectious agents in combination.
Ear canal inflammation is a common problem in small pets (10-20% in dogs and 2-6% in cats) and one of the leading reasons for visiting a veterinarian. Mitex is the perfect combination of three substances that work synergistically to provide powerful protection against otitis externa and localized skin infections. Polymyxin B and miconazole complement each other and effectively potentiate each other in their antimicrobial activity against the most important bacteria and yeast involved in otitis externa: Staphylococcus pseudointermedius, Pseudomonas aeruginosa, Escherichia coli and Malassezia pachydermatis. Prednisolone, a synthetic corticosteroids, has a rapid anti-inflammatory, antiallergic, antiexudative and antiproliferative effect and quickly relieves the symptoms of inflammation without causing systemic side effects.
Mitex has also been shown to be effective against ear mites, thus directing attention to another primary factor (specific to cats). With constant use, the parasites quickly die and the healing process is accelerated.
Indications for use
For the treatment of otitis externa and small, localized superficial skin infections in dogs and cats caused by infections with the following bacteria and fungi susceptible to miconazole and polymyxin B:
- Gram-positive bacteria: Staphylococcus spp., Streptococcus spp.
- Gram-negative bacteria: Pseudomonas spp., Escherichia coli.
- Yeasts and fungi: Malassezia pachydermatis, Candida spp., Microsporum spp., Trichophyton spp.
- Treatment of invasions of Otodectes cynotis, when there is a simultaneous infection with pathogens sensitive to miconazole and polymyxin B.
Dosage
Infections of the external auditory canal (otitis externa): 5 drops 2 times a day into the external auditory canal until several days after the complete disappearance of clinical symptoms, at least for 7-10 days to 14 days.
Concomitant infection with ear mites (Otodectes cynotis): 5 drops, 2 times a day into the external auditory canal for 14 days. Consideration should be given to treating both ears, even if the infection only occurs in one ear.
Skin infections (small, localized superficially) A few drops twice a day are well rubbed into the affected skin until several days after the complete disappearance of clinical symptoms, up to 14 days. In some persistent cases (ear or skin infections), treatment may need to be continued for 2 to 3 weeks. In cases where long-term treatment is necessary, repeated clinical examinations are necessary, including a reassessment of the diagnosis.
Packaging
Polymer bottle with a capacity of 20 ml, packed in a cardboard box.
Shelf life
2 years. In case of open packaging – 3 months.